Monday, November 3, 2008

mRNA splicing

Genes of eukaryotic cells containing introns and exons. Introns, short for intervening sequences, are non-coding regions of a gene. They are transcribed but not translated into the amino acid sequence of proteins. Exons, or expressed sequences, are coding regions of a gene and they are transcribed and translated into the amino acid sequence of proteins.
During transcription, both introns and exons are transcribed from the DNA. The primary mRNA transcript therefore contains both introns and exons.
mRNA splicing occurs and special enzymes attach to mRNA strand and the introns are cut out and the two ends of adjacent exons are then connected together. The functional mRNA molecule that is exported from the nucleus is therefore much shorter and this is the RNA that will be translated to a protein molecule.

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